Cherokee County, South Carolina

SC · FIPS 45021 Republican

Located in South Carolina, Cherokee County has a population of 56,647 residents and a median age of 40.4 years, making it the #934 most populous county out of 3,222 nationwide. In terms of economic indicators, the county has a poverty rate of 18.4%. The median home value is $142,000, and the median household income is $50,288, which is 33% below the national median.

56,647
Population
#934 of 3,222
$50,288
Median Income
-33.1% #2,756 of 3,222
40.4 years
Median Age
+3.9% #2,005 of 3,222
18.4%
Poverty Rate
+46.2% #2,512 of 3,222

Demographics

Cherokee County has a population of 56,647, making it the #934 most populous county in the US. The median age is 40.4 years, which is 3.9% above the national median.

Population Trend

Rankings →

Year-over-Year Population Growth

Age & Sex Distribution

Race & Ethnicity

Nativity

96.8%
Native Born
3.2%
Foreign Born

Geographic Mobility (Past Year)

Economy

The median household income in Cherokee County is $50,288, ranking #2,756 out of 3,222 counties — 33.1% below the national median. The poverty rate is 18.4% and unemployment stands at 6.2%.

Income#2,756
$50,288
-33.1%
vs nation
14th percentile
Per Capita#2,762
$27,406
-33.6%
vs nation
14th percentile
Poverty#2,512
18.4%
+46.2%
vs nation
22th percentile
Unemployment#2,606
6.2%
+17.7%
vs nation
19th percentile

Income Distribution

Industry of Employment

Occupation

Housing

The median home value in Cherokee County is $142,000 (-49.6% vs national). Renters pay a median of $869/mo and the homeownership rate is 73.8%.

Home Value#2,366
$142,000
-49.6%
vs nation
26th percentile
Rent#1,617
$869
-25.3%
vs nation
50th percentile
Homeownership#1,739
73.8%
+14.6%
vs nation
46th percentile

Household Type

Education

In Cherokee County, 18.4% of adults age 25+ hold a bachelor's degree or higher, which is 45.4% below the national average, ranking #2,280 out of 3,222 counties.

Bachelor's Degree or Higher
18.4% −45.4% vs nation
Rank #2,280 of 3,222
29th percentile

Bachelor's Degree or Higher Trend

Rankings →

Health & Wellbeing

Life expectancy in Cherokee County is 70.6 years. 19.9% of adults report poor or fair health and 11.5% lack health insurance. Data from County Health Rankings (2025).

Life Expectancy#2,779
70.6
-6.0%
vs nation
9th percentile
Poor/Fair Health#1,822
19.9%
+1.7%
vs nation
42th percentile
Diabetes#1,922
11.5%
+3.3%
vs nation
39th percentile
Insufficient Sleep#2,262
39.8%
+6.7%
vs nation
28th percentile
Poor Mental Health Days#1,610
5.7
+0.3%
vs nation
49th percentile
Poor Physical Health Days#1,586
4.4
-0.6%
vs nation
50th percentile
Uninsured Rate#2,029
11.5%
+9.7%
vs nation
36th percentile
Physical Inactivity#2,035
28.1%
+6.5%
vs nation
35th percentile
Food Insecurity#1,813
14.9%
+3.4%
vs nation
42th percentile

Substance Use

18.5% of adults in Cherokee County smoke , 32.3% are obese , and 18.1% report excessive drinking. The drug overdose death rate is 24.2 per 100,000.

Adult Smoking#1,840
18.5%
+3.0%
vs nation
42th percentile
Adult Obesity#357
32.3%
-14.8%
vs nation
89th percentile
Excessive Drinking#906
18.1%
-8.7%
vs nation
71th percentile
Drug Overdose Deaths#832
24.2
-25.2%
vs nation
61th percentile

Safety

The homicide rate in Cherokee County is 10.3 per 100,000 and the suicide rate is 22.7 per 100,000. Motor vehicle deaths occur at a rate of 26.9 per 100,000.

Homicide Rate#1,184
10.3
+28.9%
vs nation
23th percentile
Suicide Rate#1,886
22.7
+14.9%
vs nation
26th percentile
Firearm Fatalities#1,697
20.4
+14.3%
vs nation
31th percentile
Motor Vehicle Deaths#2,214
26.9
+32.9%
vs nation
22th percentile

Families & Children

23.5% of children in Cherokee County live in poverty and the infant mortality rate is 7.3 per 1,000 live births. The teen birth rate is 31.2 per 1,000 females age 15–19.

Infant Mortality#886
7.3
+7.1%
vs nation
35th percentile
Teen Birth Rate#2,405
31.2
+43.1%
vs nation
20th percentile
Child Poverty#2,371
23.5%
+23.7%
vs nation
25th percentile

Civic & Transportation

Voter turnout in Cherokee County is 58.7%. The mean commute time is 27.7 min, which is 0.3% above the national average.

Voter Turnout
58.7% NaN% vs nation
Rank #NaN of NaN
th percentile

Voter Turnout Trend

Mean Commute Time
27.7 min +0.3% vs nation
Rank #1,327 of 3,222
59th percentile

Mean Commute Time Trend

Rankings →

Elections

In the 2024 presidential election, Cherokee County voted Republican with a margin of 51.4%. The vote was 23.9% Dem / 75.3% Rep. Compared to 2020, the margin shifted 7.6 toward Republicans .

2024 REP +51.4%
23.9% 75.3%
Dem 24,839 votes Rep
2020 REP +43.8%
27.6% 71.4%
Dem 25,270 votes Rep
2016 REP +41.7%
28% 69.7%
Dem 21,754 votes Rep
2012 REP +29.3%
34.8% 64.1%
Dem 20,753 votes Rep
2008 REP +29.4%
34.7% 64.1%
Dem 20,766 votes Rep

Vote Share Over Time

About Cherokee County, South Carolina

Cherokee County, South Carolina has a total population of 56,647, making it the 934th most populous county in the United States. The median age in Cherokee County is 40.4 years, which is 3.9% above the national median of 38.9 years.

The median household income in Cherokee County is $50,288, which ranks #2,756 of 3,222 counties nationwide. This is 33.1% below the national median of $75,149. The poverty rate is 18.4%, higher than the national rate of 12.6%. The unemployment rate stands at 6.2%.

The median home value in Cherokee County is $142,000, 49.6% below the national median. Renters in Cherokee County pay a median gross rent of $869 per month. The homeownership rate is 73.8%, compared to the national rate of 64.4%.

In Cherokee County, 18.4% of residents aged 25 and older hold a bachelor's degree or higher, 45.4% below the national average of 33.7%. Health insurance coverage stands at 89.5% of the population. The average commute time for workers is 27.7 min.

Cherokee County is a diverse community. The largest racial or ethnic group is White (non-Hispanic) at 69.7% of the population, followed by Black (non-Hispanic) (18.7%) and Hispanic or Latino (5.5%).

All data for Cherokee County, South Carolina comes from the U.S. Census Bureau's American Community Survey (ACS) 5-Year Estimates. These figures are estimates based on survey sampling and are subject to margin of error. For the most detailed and up-to-date data, visit the Census Bureau's official data portal.