Mississippi County, Missouri

MO · FIPS 29133 Republican

Located in Missouri, Mississippi County has a population of 11,902 residents and a median age of 41.1 years, making it the #2,359 most populous county out of 3,222 nationwide. In terms of economic indicators, the county has a poverty rate of 19.0%. The median home value is $109,000, and the median household income is $48,160, which is 36% below the national median.

11,902
Population
#2,359 of 3,222
$48,160
Median Income
-35.9% #2,866 of 3,222
41.1 years
Median Age
+5.7% #1,780 of 3,222
19.0%
Poverty Rate
+51.1% #2,572 of 3,222

Demographics

Mississippi County has a population of 11,902, making it the #2,359 most populous county in the US. The median age is 41.1 years, which is 5.7% above the national median.

Population Trend

Rankings →

Year-over-Year Population Growth

Age & Sex Distribution

Race & Ethnicity

Nativity

99.6%
Native Born
0.4%
Foreign Born

Geographic Mobility (Past Year)

Economy

The median household income in Mississippi County is $48,160, ranking #2,866 out of 3,222 counties — 35.9% below the national median. The poverty rate is 19.0% and unemployment stands at 2.7%.

Income#2,866
$48,160
-35.9%
vs nation
11th percentile
Per Capita#3,011
$24,081
-41.6%
vs nation
7th percentile
Poverty#2,572
19.0%
+51.1%
vs nation
20th percentile
Unemployment#562
2.7%
-48.3%
vs nation
83th percentile

Income Distribution

Industry of Employment

Occupation

Housing

The median home value in Mississippi County is $109,000 (-61.3% vs national). Renters pay a median of $762/mo and the homeownership rate is 62.9%.

Home Value#2,866
$109,000
-61.3%
vs nation
11th percentile
Rent#2,397
$762
-34.5%
vs nation
25th percentile
Homeownership#2,861
62.9%
-2.3%
vs nation
11th percentile

Household Type

Education

In Mississippi County, 14.7% of adults age 25+ hold a bachelor's degree or higher, which is 56.3% below the national average, ranking #2,853 out of 3,222 counties.

Bachelor's Degree or Higher
14.7% −56.3% vs nation
Rank #2,853 of 3,222
11th percentile

Bachelor's Degree or Higher Trend

Rankings →

Health & Wellbeing

Life expectancy in Mississippi County is 70.0 years. 28.8% of adults report poor or fair health and 15.0% lack health insurance. Data from County Health Rankings (2025).

Life Expectancy#2,865
70.0
-6.8%
vs nation
7th percentile
Poor/Fair Health#3,031
28.8%
+47.2%
vs nation
4th percentile
Diabetes#2,730
13.7%
+23.1%
vs nation
13th percentile
Insufficient Sleep#3,053
44.6%
+19.5%
vs nation
3th percentile
Poor Mental Health Days#3,004
6.7
+18.9%
vs nation
5th percentile
Poor Physical Health Days#3,113
6.1
+35.9%
vs nation
1th percentile
Uninsured Rate#2,643
15.0%
+42.9%
vs nation
16th percentile
Physical Inactivity#3,084
37.6%
+42.5%
vs nation
2th percentile
Food Insecurity#2,973
20.2%
+40.2%
vs nation
5th percentile

Substance Use

28.9% of adults in Mississippi County smoke , 44.5% are obese , and 17.4% report excessive drinking. The drug overdose death rate is 27.0 per 100,000.

Adult Smoking#3,126
28.9%
+60.9%
vs nation
1th percentile
Adult Obesity#2,975
44.5%
+17.4%
vs nation
5th percentile
Excessive Drinking#674
17.4%
-12.3%
vs nation
79th percentile
Drug Overdose Deaths#1,000
27.0
-16.5%
vs nation
53th percentile

Safety

The homicide rate in Mississippi County is 14.3 per 100,000 and the suicide rate is 20.2 per 100,000. Motor vehicle deaths occur at a rate of 29.7 per 100,000.

Homicide Rate#1,343
14.3
+78.9%
vs nation
13th percentile
Suicide Rate#1,577
20.2
+2.5%
vs nation
38th percentile
Firearm Fatalities#2,153
26.8
+49.9%
vs nation
13th percentile
Motor Vehicle Deaths#2,379
29.7
+46.8%
vs nation
16th percentile

Families & Children

28.1% of children in Mississippi County live in poverty and the infant mortality rate is 18.5 per 1,000 live births. The teen birth rate is 45.5 per 1,000 females age 15–19.

Infant Mortality#1,363
18.5
+171.6%
vs nation
0th percentile
Teen Birth Rate#2,912
45.5
+108.5%
vs nation
3th percentile
Child Poverty#2,738
28.1%
+48.0%
vs nation
13th percentile

Civic & Transportation

Voter turnout in Mississippi County is 45.7%. The mean commute time is 23.1 min, which is 16.3% below the national average.

Voter Turnout
45.7% NaN% vs nation
Rank #NaN of NaN
th percentile

Voter Turnout Trend

Mean Commute Time
23.1 min −16.3% vs nation
Rank #2,323 of 3,222
28th percentile

Mean Commute Time Trend

Rankings →

Elections

In the 2024 presidential election, Mississippi County voted Republican with a margin of 53.7%. The vote was 22.8% Dem / 76.5% Rep. Compared to 2020, the margin shifted 4.1 toward Republicans .

2024 REP +53.7%
22.8% 76.5%
Dem 4,449 votes Rep
2020 REP +49.6%
24.8% 74.4%
Dem 4,756 votes Rep
2016 REP +41.5%
28.2% 69.7%
Dem 5,165 votes Rep
2012 REP +23.1%
37.8% 60.9%
Dem 4,918 votes Rep
2008 REP +14.6%
42% 56.6%
Dem 5,356 votes Rep

Vote Share Over Time

About Mississippi County, Missouri

Mississippi County, Missouri has a total population of 11,902, making it the 2,359th most populous county in the United States. The median age in Mississippi County is 41.1 years, which is 5.7% above the national median of 38.9 years.

The median household income in Mississippi County is $48,160, which ranks #2,866 of 3,222 counties nationwide. This is 35.9% below the national median of $75,149. The poverty rate is 19.0%, higher than the national rate of 12.6%. The unemployment rate stands at 2.7%.

The median home value in Mississippi County is $109,000, 61.3% below the national median. Renters in Mississippi County pay a median gross rent of $762 per month. The homeownership rate is 62.9%, compared to the national rate of 64.4%.

In Mississippi County, 14.7% of residents aged 25 and older hold a bachelor's degree or higher, 56.3% below the national average of 33.7%. Health insurance coverage stands at 89.1% of the population. The average commute time for workers is 23.1 min.

Mississippi County is a diverse community. The largest racial or ethnic group is White (non-Hispanic) at 70.7% of the population, followed by Black (non-Hispanic) (19.0%) and Two or More Races (8.9%).

All data for Mississippi County, Missouri comes from the U.S. Census Bureau's American Community Survey (ACS) 5-Year Estimates. These figures are estimates based on survey sampling and are subject to margin of error. For the most detailed and up-to-date data, visit the Census Bureau's official data portal.